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SMOKING is 25 per cent more likely to give women heart disease than men.
Toxic chemicals in tobacco smoke may have a more potent effect on women due to biological differences, says the shock study.
US researchers analysed pooled data on around four million people from 86 studies.
After adjusting for other factors, they found the risk of heart disease linked to smoking was 25 per cent higher for women.
The longer a woman smoked, the greater her heart disease risk compared with that of a man.
A woman's extra risk increased by two per cent for every additional year she had been smoking.
The findings were in an online edition of The Lancet medical journal yesterday.
One of the authors, Dr Rachel Huxley, of the University of Minnesota, wrote: "Women might extract a greater quantity of carcinogens and other toxic agents from the same number of cigarettes than men.
"This could explain why women who smoke have double the risk of lung cancer compared to males."
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